Monoclonal antibodies for copper-64 PET dosimetry and radioimmunotherapy

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Monoclonal antibodies for copper-64 PET dosimetry and radioimmunotherapy.

BACKGROUND We previously described a two-antibody model of (64)Cu radioimmunotherapy to evaluate low-dose, solid-tumor response. This model was designed to test the hypothesis that cellular internalization is critical in causing tumor cell death by mechanisms in addition to radiation damage. The purpose of the present study was to estimate radiation dosimetry for both antibodies (mAbs) using po...

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Monoclonal Antibodies

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ژورنال

عنوان ژورنال: Cancer Biology & Therapy

سال: 2011

ISSN: 1538-4047,1555-8576

DOI: 10.4161/cbt.11.12.15528